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Text Book of Pharmaceutical Chemistry (In Hindi) (ER2020-11T)

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Pharmaceutical chemistry is the study of drugs, and it involves drug development. This includes drug  discovery, delivery, absorption, metabolism, and more. There are elements of biomedical analysis,  pharmacology, pharmacokinetics, and pharmacodynamics. Pharmaceutical chemistry work is usually done in a lab setting. Pharmaceutical chemistry involves cures and remedies for disease, analytical techniques, pharmacology, metabolism, quality assurance, and drug chemistry. Many pharmaceutical chemistry students will later work in a lab. Pharmaceutical chemistry leads to careers in drug development, biotechnology, pharmaceutical companies, research facilities, and more.

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SKU: DP1.2 Categories: , , , ,
ISBN 978-93-91334-16-1
Publishers R. Narain Publishers & Distributors
Author Rehan Uddin, Akhilesh Yadav & Subodh Babu
Binding Paperback
Edition 1/e
Price 260
Year 2021
Pages 256
Subject Text Book of Pharmaceutical Chemistry (ER2020-12T)
Weight 250 g

Features

  1. Comprehensive coverage of theoretical and diagrammatical aspects of Pharmaceutical Chemistry.
  2. All intricate aspects are explained by simple, lucid and specific explanations and substantiated with neat and elaborate diagrammatic sketches.
  3. Examples from Pharmaceutical Chemistry are included extensively.

Table of Content

CHAPTER – 1:
Introduction to Pharmaceutical chemistry: Scope and objectives.
Sources and types of errors: Accuracy, precision, significant figures.
Impurities in Pharmaceuticals: Source and effect of impurities in Pharmacopoeial substances, importance of limit test, Principle and procedures of Limit tests for chlorides, sulphates, iron, heavy metals and arsenic.
CHAPTER – 2:
Volumetric analysis: Fundamentals of volumetric analysis, Acid-base titration, non-aqueous titration, precipitation titration, complexometric titration, redox titration
Gravimetric analysis: Principle and method.
CHAPTER – 3:
Inorganic Pharmaceuticals: Pharmaceutical formulations, market preparations, storage conditions and uses of
l Haematinics: Ferrous sulphate, Ferrous fumarate, Ferric ammonium citrate, Ferrous ascorbate, Carbonyl iron
l Gastro-intestinal Agents: Antacids, Aluminium hydroxide gel, Magnesium hydroxide, Magaldrate, Sodium bicarbonate, Calcium Carbonate, Acidifying agents, Adsorbents, Protectives, Cathartics
l Topical agents: Silver Nitrate, Ionic Silver, Chlorhexidine Gluconate, Hydrogen peroxide, Boric acid, Bleaching powder, Potassium permanganate
l Dental products: Calcium carbonate, Sodium fluoride, Denture cleaners, Denture adhesives, Mouth washes
l Medicinal gases: Carbon dioxide, nitrous oxide, oxygen
CHAPTER – 4:
Introduction to nomenclature of organic chemical systems with particular reference to heterocyclic compounds containing up to Three rings
Study of the following category of medicinal compounds with respect to classification, chemical name, chemical structure (compounds marked with*) uses, stability and storage conditions, different types of formulations and their popular brand names
CHAPTER – 5:
Drugs Acting on Central Nervous System:
l Anaesthetics: Thiopental Sodium*, Ketamine Hydrochloride*, Propofol
l Sedatives and Hypnotics: Diazepam*, Alprazolam*, Nitrazepam, Phenobarbital*
l Antipsychotics: Chlorpromazine Hydrochloride*, Haloperidol*, Risperidone*, Sulpiride*, Olanzapine, Quetiapine, Lurasidone
l Anticonvulsants: Phenytoin*, Carbamazepine*, Clonazepam, Valproic Acid*, Gabapentin*, Topiramate, Vigabatrin, Lamotrigine
l Anti-Depressants: Amitriptyline Hydrochloride*, Imipramine Hydrochloride*, Fluoxetine*, Venlafaxine, Duloxetine, Sertraline, Citalopram, Escitalopram, Fluvoxamine, Paroxetine.
CHAPTER – 6:
Drugs Acting on Autonomic Nervous System
l Sympathomimetic Agents: Direct Acting: Nor- Epinephrine*, Epinephrine, Phenylephrine, Dopamine*, Terbutaline, Salbutamol (Albuterol), Naphazoline*, Tetrahydrozoline.
l Indirect Acting Agents: Hydroxy Amphetamine, Pseudoephedrine. Agents With Mixed Mechanism: Ephedrine, Metaraminol
l Adrenergic Antagonists: Alpha Adrenergic Blockers: Tolazoline, Phentolamine
l Phenoxybenzamine, Prazosin. Beta Adrenergic Blockers: Propranolol*, Atenolol*, Carvedilol
l Cholinergic Drugs and Related Agents: Direct Acting Agents: Acetylcholine*, Carbachol, And Pilocarpine. Cholinesterase Inhibitors: Neostigmine*, Edrophonium Chloride, Tacrine Hydrochloride, Pralidoxime Chloride, Echothiopate Iodide
l Cholinergic Blocking Agents: Atropine Sulphate*, Ipratropium Bromide Synthetic Cholinergic Blocking Agents: Tropicamide, Cyclopentolate Hydrochloride, Clidinium Bromide, Dicyclomine Hydrochloride*
CHAPTER – 7:
Drugs Acting on Cardiovascular System:
l Anti-Arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Verapamil, Phenytoin Sodium*, Lidocaine Hydrochloride, Lorcainide Hydrochloride, Amiodarone and Sotalol
l Anti-Hypertensive Agents: Propranolol*, Captopril*, Ramipril, Methyldopate Hydrochloride, Clonidine Hydrochloride, Hydralazine Hydrochloride, Nifedipine,
l Antianginal Agents: Isosorbide Dinitrate.
CHAPTER – 8:
Diuretics: Acetazolamide, Frusemide*, Bumetanide,
Chlorthalidone, Benzthiazide, Metolazone, Xipamide, Spironolactone.
CHAPTER – 9:
Hypoglycemic Agents: Insulin and Its Preparations, Metformin*, Glibenclamide*, Glimepiride, Pioglitazone,
Repaglinide, Gliflozins, Gliptins.
CHAPTER – 10:
Analgesic And Anti-Inflammatory Agents: Morphine Analogues, Narcotic Antagonists; Nonsteroidal Anti – Inflammatory Agents (NSAIDs) – Aspirin*, Diclofenac, Ibuprofen*, Piroxicam, Celecoxib, Mefenamic Acid, Paracetamol*, Aceclofenac.
CHAPTER – 11:
Anti-Infective Agents
l Antifungal Agents: Amphotericin-B, Griseofulvin, Miconazole, Ketoconazole*, Itraconazole, Fluconazole*, Naftifine Hydrochloride.
l Urinary Tract Anti-Infective Agents: Norfloxacin, Ciprofloxacin, Ofloxacin*, Moxifloxacin,
l Anti-Tubercular Agents: INH*, Ethambutol, Para Amino Salicylic Acid, Pyrazinamide, Rifampicin, Bedaquiline, Delamanid, Pretomanid*
l Antiviral Agents: Amantadine Hydrochloride, Idoxuridine, Acyclovir*, Foscarnet, Zidovudine, Ribavirin, Remdesivir, Favipiravir
l Antimalarials: Quinine Sulphate, Chloroquine Phosphate*, Primaquine Phosphate, Mefloquine*, Cycloguanil, Pyrimethamine, Artemisinin
l Sulfonamides: Sulfanilamide, Sulfadiazine, Sulfametho xazole, Sulfacetamide*, Mafenide Acetate, Cotrimoxazole, Dapsone*
CHAPTER – 12:
Antibiotics: Penicillin G, Amoxicillin*, Cloxacillin, Streptomycin, Tetracyclines: Doxycycline, Minocycline, Macrolides: Erythromycin, Azithromycin, Miscellaneous: Chloramphenicol* Clindamycin.
CHAPTER – 13:
Anti-Neoplastic Agents: Cyclophosphamide*, Busulfan, Mercaptopurine, Fluorouracil*, Methotrexate, Dactinomycin, Doxorubicin Hydrochloride, Vinblastine Sulphate, Cisplatin*, Dromostanolone Propionate.

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