|Publishers||R. Narain Publishers & Distributors|
|Author||Rehan Uddin & Saharukh Khan|
|Subject||Text Book of Biochemistry & Clinical Pathology (In Hindi) (ER2020-23T)|
Text Book of Biochemistry & Clinical Pathology (In Hindi) (ER2020-23T)
Biochemistry & Clinical Pathology is a core subject in D. Pharm, which is taught in the second year. It is the branch of pharmacy that deals with the process of converting a novel chemical entity (NCE) or an existing medicine into a medication that patients may use safely and efficiently. It’s also known as dosage form design science where a student learns various techniques of developing a formulation. Many compounds have pharmacological characteristics, but many require specific handling to obtain therapeutically relevant concentrations at their areas of action. Pharmaceutics aids in the connection between medication formulation, distribution and disposal in the body.
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Estimated Delivery for Rural Areas 5 to 7 Days
Table of Content
. Introduction to biochemistry: Scope of biochemistry in pharmacy; Cell and its biochemical organization.
Definition, classification with examples, chemical properties
Monosaccharides – Structure of glucose, fructose, and galactose
Disaccharides – structure of maltose, lactose, and sucrose
Polysaccharides – chemical nature of starch and glycogen
Qualitative tests and biological role of carbohydrates
Definition, classification of proteins based on composition and solubility with examples
Definition, classification of amino acids based on chemical nature and nutritional requirements with examples
Structure of proteins (four levels of organization of protein structure)
Qualitative tests and biological role of proteins and amino acids
Diseases related to malnutrition of proteins.
Definition, classification with examples
Structure and properties of triglycerides (oils and fats)
Fatty acid classification- Based on chemical and nutritional requirements with examples
Structure and functions of cholesterol in the body
Lipoproteins – types, composition and functions in the body
Qualitative tests and functions of lipids
- Nucleic acids
Definition, purine and pyrimidine bases
Components of nucleosides and nucleotides with examples
Factors affecting enzyme activity
l Mechanism of action of enzymes, Enzyme inhibitors
l Therapeutic and pharmaceutical importance of enzymes
Definition and classification with examples
Sources, chemical nature, functions, coenzyme form, recommended dietary requirements, deficiency diseases of fat-and water-soluble vitamins
(Study of cycle/pathways without chemical structures)
Metabolism of Carbohydrates: Glycolysis, TCA cycle and glycogen metabolism, regulation of blood glucose level. Diseases related to abnormal metabolism of Carbohydrates
Metabolism of lipids: Lipolysis, â-oxidation of Fatty acid (Palmitic acid) ketogenesis and ketolysis. Diseases related to abnormal metabolism of lipids such as Ketoacidosis, Fatty liver, Hypercholesterolemia
Metabolism of Amino acids (Proteins): General reactions of amino acids and its significance– Transamination, deamination, Urea cycle and decarboxylation. Diseases related to abnormal metabolism of amino acids, Disorders of ammonia metabolism, phenylketonuria, alkaptonuria and Jaundice.
Biological oxidation: Electron transport chain and Oxidative phosphorylation.
- Minerals: Types, Functions, Deficiency diseases, recommended dietary requirements
- Water and Electrolytes
Distribution, functions of water in the body
Water turnover and balance
Electrolyte composition of the body fluids, Dietary intake of electrolyte and Electrolyte balance
Dehydration, causes of dehydration and oral rehydration therapy
- Introduction to Biotechnology
- Organ function tests
Functions of kidney and routinely performed tests to assess the functions of kidney and their clinical significances
Functions of liver and routinely performed tests to assess the functions of liver and their clinical significances
Lipid profile tests and its clinical significances.
- Introduction to Pathology of Blood and Urine
Lymphocytes and Platelets, their role in health and disease
Erythrocytes – Abnormal cells and their significance
Normal and Abnormal constituents of Urine and their significance.
- Comprehensive coverage of theoretical and diagrammatical aspects of pharmaceutics.
- All intricate aspects are explained by simple, lucid and specific explanations and substantiated with neat and elaborate diagrammatic sketches.
- Examples from pharmaceutics are included extensively.
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