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Text Book of Biochemistry & Clinical Pathology (In Hindi) (ER2020-23T)

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Biochemistry & Clinical Pathology is a core subject in D. Pharm, which is taught in the second year. It is the branch of pharmacy that deals with the process of converting a novel chemical entity (NCE) or an existing medicine into a medication that patients may use safely and efficiently. It’s also known as dosage form design science where a student learns various techniques of developing a formulation. Many compounds have pharmacological characteristics, but many require specific handling to obtain therapeutically relevant concentrations at their areas of action. Pharmaceutics aids in the connection between medication formulation, distribution and disposal in the body.

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SKU: DPH2.3 Categories: , , , ,
ISBN 978-93-91334-19-2
Publishers R. Narain Publishers & Distributors
Author Rehan Uddin & Saharukh Khan
Binding Paperback
Edition 1/e
Price 180
Year 2021
Pages 144
Subject Text Book of Biochemistry & Clinical Pathology (In Hindi) (ER2020-23T)
Weight 150 g

Table of Content

.     Introduction  to  biochemistry:  Scope of  biochemistry  in pharmacy; Cell and  its biochemical organization.

  1. Carbohydrates

Definition, classification with examples, chemical properties

Monosaccharides – Structure of glucose, fructose, and galactose

Disaccharides   Р structure  of  maltose,   lactose,   and sucrose

Polysaccharides¬† ¬†–¬† ¬†chemical¬† ¬†nature ¬†of¬† ¬†starch ¬†and glycogen

Qualitative tests and  biological role of carbohydrates

  1. Proteins

Definition, classification of proteins based on composition and  solubility with examples

Definition,   classification   of   amino   acids   based  on chemical nature and  nutritional requirements with examples

Structure  of  proteins  (four   levels  of  organization  of protein structure)

Qualitative  tests and   biological  role  of  proteins  and amino acids

Diseases related to malnutrition of proteins.

  1. Lipids

Definition, classification with examples

Structure and  properties of triglycerides (oils and  fats)

Fatty acid classification- Based on chemical and nutritional requirements with examples

Structure and  functions of cholesterol in the body

Lipoproteins  Рtypes, composition  and  functions  in  the body

Qualitative tests and functions of lipids

  1. Nucleic acids

Definition, purine and  pyrimidine bases

Components of nucleosides and nucleotides with examples

Factors affecting enzyme activity

l    Mechanism of action of enzymes, Enzyme inhibitors

l    Therapeutic and           pharmaceutical importance of enzymes

  1. Vitamins

Definition and classification with examples

Sources, chemical  nature, functions,  coenzyme form, recommended  dietary  requirements,  deficiency diseases of fat-and water-soluble vitamins

  1. Metabolism

(Study   of  cycle/pathways  without chemical structures)

Metabolism  of  Carbohydrates:  Glycolysis,  TCA  cycle and  glycogen  metabolism,  regulation  of blood  glucose level.   Diseases   related   to  abnormal   metabolism   of Carbohydrates

Metabolism of lipids: Lipolysis, √Ę-oxidation of Fatty acid (Palmitic acid) ketogenesis and ketolysis. Diseases related to abnormal metabolism of lipids such as Ketoacidosis, Fatty liver, Hypercholesterolemia

Metabolism¬†¬† ¬†of¬†¬† ¬†Amino¬†¬† ¬†acids¬†¬† ¬†(Proteins):¬†¬† ¬†General reactions of amino acids and its significance‚Äď Transamination, deamination, Urea cycle and decarboxylation. Diseases related to abnormal metabolism of amino acids, Disorders of ammonia metabolism,¬† phenylketonuria,¬† alkaptonuria ¬†and Jaundice.

Biological     oxidation:       Electron     transport      chain and     Oxidative phosphorylation.

  1. Minerals: Types, Functions, Deficiency diseases, recommended dietary requirements
  2. Water and Electrolytes

Distribution, functions of water  in the body

Water turnover  and balance

Electrolyte   composition   of   the   body   fluids,   Dietary intake of electrolyte and  Electrolyte balance

Dehydration, causes of dehydration and oral rehydration therapy

  1. Introduction to Biotechnology
  2. Organ function tests

Functions  of kidney  and  routinely  performed  tests to assess the functions of kidney and  their clinical significances

Functions  of  liver  and   routinely  performed  tests  to assess the  functions  of  liver  and  their  clinical significances

Lipid profile tests and  its clinical significances.

  1. Introduction to Pathology of Blood and Urine

Lymphocytes  and   Platelets,  their  role  in  health  and disease

Erythrocytes РAbnormal cells and  their significance

Normal  and  Abnormal  constituents  of Urine  and  their significance.

Features

  1. Comprehensive coverage of theoretical and diagrammatical aspects of pharmaceutics.
  2. All intricate aspects are explained by simple, lucid and specific explanations and substantiated with neat and elaborate diagrammatic sketches.
  3. Examples from pharmaceutics are included extensively.

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