Text Book of Biochemistry & Clinical Pathology (ER2020-23T)

pharmacy; Cell and  its biochemical organization.

   Definition,      classification        with     examples,      chemical properties

   Monosaccharides – Structure of glucose, fructose, and galactose

   Disaccharides   –  structure  of  maltose,   lactose,   and sucrose

   Polysaccharides   –   chemical   nature  of   starch  and glycogen

   Qualitative tests and  biological role of carbohydrates

   Definition,     classification     of    proteins     based    on composition and  solubility with examples

   Definition,   classification   of   amino   acids   based  on chemical nature and  nutritional requirements with examples

   Structure  of  proteins  (four   levels  of  organization  of protein structure)

   Qualitative  tests and   biological  role  of  proteins  and amino acids

   Diseases related to malnutrition of proteins.

   Definition, classification with examples

   Structure and  properties of triglycerides (oils and  fats)

   Fatty   acid     classification – Based                on

chemical        and      nutritional         requirements          with examples

   Structure and  functions of cholesterol in the body

   Lipoproteins  – types, composition  and  functions  in  the body

   Qualitative tests and functions of lipids

   Definition, purine and  pyrimidine bases

   Components       of     nucleosides      and    nucleotides     with examples

   Structure of DNA (Watson and  Crick model), RNA and their functions

   Definition, properties and  IUB and  MB classification

   Factors affecting enzyme activity

   Mechanism of action of enzymes, Enzyme inhibitors

   Therapeutic        and      pharmaceutical        importance       of enzymes

   Definition and classification with examples

   Sources, chemical  nature, functions,  coenzyme form, recommended  dietary  requirements,  deficiency diseases of fat-and water-soluble vitamins

structures)

   Metabolism  of  Carbohydrates:  Glycolysis,  TCA  cycle and  glycogen  metabolism,  regulation  of blood  glucose

Carbohydrates

   Metabolism of lipids: Lipolysis, β-oxidation of Fatty acid (Palmitic acid) ketogenesis and ketolysis. Diseases related to abnormal metabolism of lipids such as Ketoacidosis, Fatty liver, Hypercholesterolemia

   Metabolism    of    Amino    acids    (Proteins):    General reactions of amino acids and its significance– Transamination, deamination, Urea cycle and decarboxylation. Diseases related to abnormal metabolism of amino acids, Disorders of ammonia metabolism,  phenylketonuria,  alkaptonuria  and Jaundice.

   Biological     oxidation:       Electron     transport      chain and     Oxidative phosphorylation

recommended dietary requirements

   Distribution, functions of water  in the body

   Water turnover  and balance

   Electrolyte   composition   of   the   body   fluids,   Dietary intake of electrolyte and  Electrolyte balance

   Dehydration,       causes      of       dehydration       and      oral rehydration therapy

   Functions  of kidney  and  routinely  performed  tests to assess the functions of kidney and  their clinical significances

   Functions  of  liver  and   routinely  performed  tests  to assess the  functions  of  liver  and  their  clinical significances

   Lipid profile tests and  its clinical significances

   Lymphocytes  and   Platelets,  their  role  in  health  and disease

   Erythrocytes – Abnormal cells and  their significance

   Normal  and  Abnormal  constituents  of Urine  and  their significance